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Calcium Rosuvastatin (BANM, JAN, USAN) ni a mọ ni Rosuvastatin ni AMẸRIKA.ati ifigagbaga HMG-CoA reductase inhibitor pẹlu IC50 ti 11 nM[1].Calcium Rosuvastatin ni agbara ti o ṣe idiwọ jiini ti o ni ibatan ether-a-go-go eniyan (hERG) lọwọlọwọ pẹlu IC50 ti 195 nM, idaduro isọdọtun ọkan ọkan, ati nitorinaa awọn akoko agbara ṣiṣe gigun (APDs) ati atunse aarin aarin QTc (QTc) [2].Calcium Rosuvastatin dinku ikosile ti hERG ti o dagba ati ibaraenisepo ti amuaradagba mọnamọna ooru 70 (Hsp70) pẹlu amuaradagba hERG.Calcium Rosuvastatin munadoko pupọ ni idinku lipoprotein iwuwo kekere (LDL) idaabobo awọ, triglycerides, ati awọn ipele amuaradagba C-reactive[3].

Alaye siwaju sii lori awọn apejọ isorukọsilẹ oogun: Awọn Orukọ Alailowaya Kariaye.

Akiyesi Pataki: Data data ilu okeere Drugs.com wa ninu itusilẹ BETA.Eyi tumọ si pe o tun wa labẹ idagbasoke ati pe o le ni awọn aiṣedeede ninu.Ko ṣe ipinnu bi aropo fun oye ati idajọ ti dokita rẹ, oloogun tabi alamọdaju ilera miiran.Ko yẹ ki o tumọ lati fihan pe lilo oogun eyikeyi ni orilẹ-ede eyikeyi jẹ ailewu, yẹ tabi munadoko fun ọ.Kan si alagbawo pẹlu alamọdaju ilera rẹ ṣaaju ki o to mu oogun eyikeyi.

Ni AMẸRIKA, Rosuvastatin (systemic rosuvastatin) jẹ ọmọ ẹgbẹ ti oogun oogun statins ati pe a lo lati ṣe itọju Atherosclerosis, Cholesterol giga, Cholesterol giga - Heterozygous idile, Cholesterol giga - Homozygous idile, Hyperlipoproteinemia, Hyperlipoproteinemia Iru IIa - Ilọsiwaju LDL, Iru LDL, Hyperlipoproteinemia. IIb - LDL VLDL ti o ga, Hyperlipoproteinemia Iru III - Beta-VLDL IDL ti o ga, Hyperlipoproteinemia Iru IV - VLDL ti o ga, Hypertriglyceridemia ati Idena Arun Arun inu ọkan.

abẹlẹ

Ayanfẹ, oludaniloju ifigagbaga ti HMG-CoA reductase, iyẹn tun jẹ antilipemic.

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