Crisaborole

Apejuwe kukuru:

Orukọ API Itọkasi Innovator Ọjọ Itọsi Itọsi (AMẸRIKA)
Crisaborole Atopic Dermatitis ati Àléfọ Pfizer Oṣu Kẹfa Ọjọ 11, Ọdun 2026 


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Apejuwe ọja

Crisaborole jẹ ọmọ ẹgbẹ ti kilasi ti benzoxaboroles ti o jẹ 5-hydroxy-1,3-dihydro-2,1-benzoxaborole ninu eyiti phenolic.hydrogenti rọpo nipasẹ ẹgbẹ 4-cyanophenyl.Inhibitor phosphodiesterase 4 ti a lo fun itọju ti ìwọnba si dede atopic dermatitis ninu awọn ọmọde ati awọn agbalagba.O ni ipa kan bi oludena phosphodiesterase IV, ẹyaantipsoriaticati oogun egboogi-iredodo ti kii-sitẹriọdu.O jẹ benzoxaborole, ether ti oorun didun ati nitrile kan.

Crisaborole jẹ aramadaoxaborolefọwọsi nipasẹ FDA ni Oṣu Kejila ọjọ 14, Ọdun 2016 bi Eucrisa, itọju ti agbegbe fun ìwọnba ati iwọntunwọnsi atopic dermatitis.Oluranlọwọ ti kii ṣe sitẹriọdu yii jẹ imudara ni imudarasi ibajẹ arun, idinku eewu ikolu ati idinku awọn ami ati awọn ami aisan ni awọn alaisan ti o jẹ ọdun 2 ati agbalagba.O dinku igbona agbegbe ni awọ ara ati idilọwọ ilọsiwaju siwaju sii ti arun na pẹlu profaili aabo to dara.Ilana rẹ ni aboronatomu, eyi ti o ṣe iranlọwọ fun ilaluja awọ ara ati isopọmọ si aarin bimetal ti phosphodiesterase 4 enzymu.Lọwọlọwọ o wa labẹ idagbasoke bi itọju agbegbe ti psoriasis.

Crisaborole jẹ oludena Phosphodiesterase 4.Ilana iṣe ti crisaborole jẹ bi oludena phosphodiesterase 4.

Ijẹrisi

2018 GMP-2
原料药GMP证书201811(captopril ,thalidomide etc)
GMP-of-PMDA-in-Chanyoo-平成28年08月03日 Nantong-Chanyoo-Pharmatech-Co
FDA-EIR-Letter-201901

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Igbero18Awọn iṣẹ akanṣe Igbelewọn Iṣeduro Didara eyiti o ti fọwọsi4, ati6ise agbese ni o wa labẹ alakosile.

Quality management2

Eto iṣakoso didara agbaye ti ilọsiwaju ti fi ipilẹ to lagbara fun tita.

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Abojuto didara n ṣiṣẹ nipasẹ gbogbo igbesi aye ọja lati rii daju didara ati ipa itọju ailera.

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