Chlorothiazide

Apejuwe kukuru:

Orukọ API Itọkasi Sipesifikesonu US DMF EU DMF CEP
Chlorothiazide Diuretics USP/EP      


Alaye ọja

ọja Tags

Apejuwe ọja

abẹlẹ

Chlorothiazide jẹ inhibitor ti carbonic anhydrase ati pe o kere diẹ si agbara ju acetazolamide.A ti ṣe afihan agbo-ara yii lati dènà isọdọtun ti iṣuu soda ati awọn ions kiloraidi.

Apejuwe

Chlorothiazide jẹ diuretic ati antihypertensive.(IC50=3.8 mM) Ifojusi: Awọn omiiran Chlorothiazide sodium (Diuril) jẹ diuretic ti a lo laarin eto ile-iwosan tabi fun lilo ti ara ẹni lati ṣakoso omi ti o pọ ju ti o ni nkan ṣe pẹlu ikuna ọkan iṣọn.O tun lo bi antihypertensive.Nigbagbogbo ti a mu ni fọọmu egbogi, a maa n mu ni ẹnu lẹẹkan tabi lẹmeji ni ọjọ kan.Ni eto ICU, chlorothiazide ni a fun lati diurese alaisan ni afikun si furosemide (Lasix).Ṣiṣẹ ni ọna ti o yatọ ju furosemide, ati gbigba sinu titẹ bi idadoro ti a tun ṣe ti a nṣakoso nipasẹ tube nasogastric ( tube NG), awọn oogun meji n mu ara wọn lagbara.

Iwadii isẹgun

Nọmba NCT Onigbowo Ipo Ọjọ Ibẹrẹ

Ipele

NCT03574857 Yunifasiti ti Virginia Ikuna Okan|Ikuna Okan Pẹlu Idinku Idinku Ejection|Ikuna Ọkàn | Awọn Arun inu ọkan ati ẹjẹ Oṣu Kẹfa ọdun 2018

Ipele 4

NCT02546583 Ile-ẹkọ giga Yale | Okan ti Orilẹ-ede, Ẹdọfóró, ati Ile-ẹkọ Ẹjẹ (NHLBI) Ikuna Okan Oṣu Kẹjọ Ọdun 2015

Ko ṣiṣẹ fun

NCT02606253 Ile-ẹkọ giga Vanderbilt | Ile-iṣẹ iṣoogun ti Ile-ẹkọ giga Vanderbilt Ikuna Okan Oṣu Kẹta ọdun 2016

Ipele 4

NCT00004360 Ile-iṣẹ Orilẹ-ede fun Awọn orisun Iwadi (NCRR) | Ile-ẹkọ giga Ariwa iwọ-oorun | Ọfiisi ti Awọn Arun Rare (ORD) Àtọgbẹ Insipidus, Nephrogenic Oṣu Kẹsan 1995

NCT00000484 Okan ti Orilẹ-ede, Ẹdọfóró, ati Ile-ẹkọ Ẹjẹ (NHLBI) Àwọn Àrùn Ẹ̀dọ̀ Àrùn |Àwọn àrùn ọkàn Oṣu Kẹrin ọdun 1966

Ipele 3

Ilana kemikali

Chlorothiazide

Ijẹrisi

2018 GMP-2
原料药GMP证书201811(captopril ,thalidomide etc)
GMP-of-PMDA-in-Chanyoo-平成28年08月03日 Nantong-Chanyoo-Pharmatech-Co
FDA-EIR-Letter-201901

Ìṣàkóso didara

Quality management1

Igbero18Awọn iṣẹ akanṣe Igbelewọn Iṣeduro Didara eyiti o ti fọwọsi4, ati6ise agbese ni o wa labẹ alakosile.

Quality management2

Eto iṣakoso didara agbaye ti ilọsiwaju ti fi ipilẹ to lagbara fun tita.

Quality management3

Abojuto didara n ṣiṣẹ nipasẹ gbogbo igbesi aye ọja lati rii daju didara ati ipa itọju ailera.

Quality management4

Ẹgbẹ Aṣoju Iṣeduro Ọjọgbọn ṣe atilẹyin awọn ibeere didara lakoko ohun elo ati iforukọsilẹ.

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Domestic cooperation

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