Baloxavir Marboxil 1985606-14-1
abẹlẹ
Baloxavir marboxil jẹ oogun apakokoro ati pe o jẹ onidalẹkun endonuclease.Ninu awọn eku ati awọn obo, ifọkansi ẹjẹ ti oogun naa kere ju iye wiwa ti o kere ju ninu iṣakoso ẹnu kan ti oogun naa.Ni aarun ayọkẹlẹ aarun ayọkẹlẹ A ati awọn awoṣe ikolu B (pẹlu awọn igara ti o sooro si awọn oogun ọlọjẹ ti o wa tẹlẹ), Baloxavir marboxil ni ipa kan.
Kemikali Properties
| Ibi ipamọ | Fipamọ ni -20°C |
| M.Wt | 571.55 |
| Cas No. | 1985606-14-1 |
| Fọọmu | C27H23F2N3O7S |
| Awọn itumọ ọrọ sisọ | S-033188 |
| Solubility | Tiotuka ni DMSO |
| Orukọ Kemikali | ((R) -12-((S) -7,8-difluoro-6,11-dihydrodibenzo[b,e] thiepin-11-yl)-6,8-dioxo-3,4,6,8, 12,12a-hexahydro-1H- [1,4] oxazino [3,4-c] pyrido [2,1-f] [1,2,4] triazin-7-yl) oxy) methyl carbonate carbonate |
| SDF | Ṣe igbasilẹ SDF |
| Ẹ̀RẸ̀ KẸ̀RÁN | O=C1C=CN(N([C@]2(N(C3=O)CCOC2)[H])[C@H]4C5=CC=C(C(F)=C5CSC6=CC=CC=C46) F)C3=C1OCOC(OC)=O |
| Sowo Ipò | Ojutu ayẹwo ayẹwo: ọkọ oju omi pẹlu yinyin buluu.Gbogbo awọn titobi miiran ti o wa: ọkọ pẹlu RT, tabi yinyin buluu lori ibeere. |
| Gbogbogbo awọn italolobo | Fun gbigba solubility ti o ga julọ, jọwọ gbona tube ni 37 ° C ki o si gbọn ni iwẹ ultrasonic fun igba diẹ.Ojutu ọja le wa ni ipamọ ni isalẹ -20 ° C fun ọpọlọpọ awọn oṣu. |
Ilana kemikali
Igbero18Awọn iṣẹ akanṣe Igbelewọn Iṣeduro Didara eyiti o ti fọwọsi4, ati6ise agbese ni o wa labẹ alakosile.
Eto iṣakoso didara agbaye ti ilọsiwaju ti fi ipilẹ to lagbara fun tita.
Abojuto didara n ṣiṣẹ nipasẹ gbogbo igbesi aye ọja lati rii daju didara ati ipa itọju ailera.
Ẹgbẹ Aṣoju Iṣeduro Ọjọgbọn ṣe atilẹyin awọn ibeere didara lakoko ohun elo ati iforukọsilẹ.
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