Doxycycline Hyclate
abẹlẹ
Doxycycline hyclate jẹ apakokoro [1].
Doxycycline hyclate jẹ itọsẹ ti tetracycline ati pe o ni awọn iṣe ti egboogi-iredodo ati antimicrobial.Doxycycline ṣe idiwọ ẹda dengue kokoro ni fitiro pẹlu ọna ti o gbẹkẹle iwọn otutu.Iye IC50 jẹ 52.3μM ni 37°C ati 26.7μM ni 40°C.O ṣe idiwọ ọlọjẹ dengue nipasẹ didi protease serine NS2B-NS3 ti ọlọjẹ naa.60μM doxycycline dinku CPE ti awọn sẹẹli ti o ni arun DNEV2 [1].
Doxycycline ni a rii lati jẹ onidalẹkun ti MMP.Itọju Doxycycline dinku awọn ipele MMP-8 ati -9 ati idilọwọ ikosile ti àsopọ MMP-2 ati MMP-9.Pẹlupẹlu, itọju pẹlu doxycycline ni pataki dinku iṣẹlẹ ti aneurysms intracranial.Doxycycline tun ti royin lati jẹ aṣoju egboogi-iredodo ti o da lori idinamọ rẹ ti matrix metalloproteinases.Ni afikun, doxycycline ni iṣẹ antimalarial ti o lagbara pẹlu iye IC50 ti 320nM ni 96h in vitro [2, 3].
Awọn itọkasi:
[1] Rothan HA, Mohamed Z, Paydar M, Rahman NA, Yusof R. Ipa idilọwọ ti doxycycline lodi si ẹda dengue kokoro ni vitro.Arch Virol.2014 Oṣu Kẹrin; 159 (4): 711-8.
[2] Maradni A, Khoshnevisan A, Mousavi SH, Emamirazavi SH, Noruzijavidan A. Ipa ti matrix metalloproteinases (MMPs) ati awọn oludena MMP lori awọn aneurysms intracranial: akọsilẹ atunyẹwo.Med J Islam Repub Iran.2013 Kọkànlá Oṣù; 27 (4): 249-254.
[3] Draper MP, Bhatia B, Assefa H, Honeyman L, Garrity-Ryan LK, Verma AK, Gut J, Larson K, Donatelli J, Macone A, Klausner K, Leahy RG, Odinecs A, Ohemeng K, Rosenthal PJ, Nelson ML.In vitro ati in vivo awọn ipa antimalarial ti iṣapeye tetracyclines.Awọn aṣoju Antimicrob Chemother.2013 Jul; 57 (7): 3131-6.
Apejuwe
Doxycycline (hyclate) (Doxycycline hydrochloride hemiethanolate hemihydrate), apakokoro, jẹ ohun ti nṣiṣe lọwọ ẹnu ati ki o gbooro-spekitiriumu metalloproteinase (MMP) inhibitor[1].
Iwadii isẹgun
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NCT03153267 | Ile-iṣẹ Iṣoogun ti Ile-ẹkọ giga Ljubljana | Ile-ẹkọ giga ti Ile-ẹkọ Oogun Ljubljana, Slovenia | Erythema Chronicum Migrans | Oṣu Kẹfa Ọjọ 1, Ọdun 2017 | Ko ṣiṣẹ fun |
NCT03116659 | James J. Peters Veterans Affairs Medical Center | Lymphoma, T-Cell, Cutaneous | Oṣu Kẹta Ọjọ 1, Ọdun 2018 | Ipele Ibẹrẹ 1 |
NCT03401372 | Jian Li | Ile-iwosan akọkọ ti Ile-ẹkọ giga Peking | Ile-iwosan Gbogbogbo PLA Ilu Kannada | Ile-iwosan Beijing Chao Yang | Ile-iwosan Iwọ-oorun China ti o somọ pẹlu Ile-ẹkọ giga Sichuan | Ile-iwosan Tongji Ti o ni ibatan pẹlu Ile-ẹkọ Iṣoogun Tongji ti HUST Ile-iwosan Nanfang ti Ile-ẹkọ Iṣoogun ti Gusu | Ile-iwosan Ile-ẹkọ Iṣoogun ti Peking Union | Amyloidosis;Eto eto | Oṣu Kẹrin Ọjọ 21, Ọdun 2018 | Ko ṣiṣẹ fun |
NCT01380496 | Par Pharmaceutical, Inc.|Anapharm | Lati pinnu Bioequivalence Labẹ Awọn ipo Je | Oṣu kọkanla ọdun 1999 | Ipele 1 |
NCT03083197 | Yunifasiti ti Oxford | Ẹka Iwadi Iba Shoklo | Ile-iwosan Chiangrai Prachanukroh | Scrub Typhus | Oṣu Kẹjọ Ọjọ 15, Ọdun 2017 | Ipele 4 |
NCT00237016 | Medical Corps, Israeli Aabo Force | Ìbà Ìfàséyìn, Tick-Borne|Ìṣe Jarisch Herxheimer | Oṣu Kẹrin ọdun 2002 | Ipele 2 |Ibala 3 |
NCT01308619 | Galderma Laboratories, LP | Rosacea | Oṣu Kẹrin Ọjọ 2011 | Ipele 4 |
NCT01198912 | Ile-iwosan University, Ghent | Chronic Rhinosinusitis|Àwọn Polyps Imú | Oṣu kọkanla ọjọ 22, Ọdun 2011 | Ipele 2 |
NCT02016365 | Ile-ẹkọ giga Umeå | Transthyretin Amyloidosis|Cardiomyopathy | Oṣu Kẹta ọdun 2012 | Ipele 2 |
NCT00783523 | Yunifasiti ti California, San Francisco | Awọn Ẹjẹ Arun Ẹjẹ | Awọn Angiomas Cavernous | Awọn Aneurysms Ọpọlọ | Oṣu Kẹta Ọdun 2008 | Ipele 1 |
NCT03337932 | University Medical Center Ljubljana | Erythema Chronicum Migrans | Oṣu Kẹta ọjọ 1, Ọdun 2018 | Ko ṣiṣẹ fun |
NCT00568711 | Dong-Min Kim | Ile-iwosan Yunifasiti Chosun | Scrub Typhus | Oṣu Kẹsan 2006 | Ko ṣiṣẹ fun |
NCT01874860 | Ile-ẹkọ giga ti Louisville | Ile-iṣẹ Akàn James Graham Brown | Akàn Àrùn | Ori ati Ọrun | Oṣu Kẹjọ Ọdun 2013 | Ipele 2 |
NCT01171859 | IRCCS Policlinico S. Matteo | Amyloidosis transthyretin | Oṣu Keje Ọdun 2010 | Ipele 2 |
NCT01653522 | Ile-iwosan Cleveland | Ìbànújẹ́ Migraine|Ẹ̀fọ́rí, Migraine|Migraine|Orífọ́rí|Ìjìnlẹ̀ Pẹ̀lú Aura|Ìjìnlẹ̀ Láìsí Aura|Àwọn Ẹ̀fọ́rí, Àkọ́kọ́ | Oṣu Keje ọdun 2012 | Ko ṣiṣẹ fun |
NCT01820910 | Ẹgbẹ Ikẹkọ Lymphoma Extranodal International (IELSG) | Aini agbegbe Lymphoma ti Ocular Adnexal | Oṣu Kẹta ọdun 2013 | Ipele 2 |
NCT01323101 | University of Southern California | Cystic Fibrosis | Oṣu Kẹrin Ọjọ 2008 | Ipele 4 |
NCT00829764 | Teva Pharmaceuticals USA | Ni ilera | Oṣu Kẹwa Ọdun 2006 | Ipele 1 |
NCT01668498 | AIO-Studien-gGmbH | Ras-wildtype Colorectal akàn | Oṣu Karun ọdun 2011 | Ipele 2 |
NCT01030666 | Peter Eickholz|Ile-ẹkọ giga Heidelberg|Dr.August Wolff GmbH & Co. KG Arzneimittel|Gaba International AG| University Goethe | Periodontitis | Oṣu Kẹrin Ọjọ 2007 | Ipele 4 |
NCT00012688 | Ẹka AMẸRIKA ti Awọn ọran Awọn Ogbo |Colgate-Periogard-Dentsply|Ọfiisi VA ti Iwadi ati Idagbasoke | Àtọgbẹ mellitus|Iṣakoso Glycemic Ko dara | Ko ṣiṣẹ fun | |
NCT01885910 | Derm Research, PLLC|WFH MEDICAL, LLC | Irorẹ vulgaris | Oṣu Keje ọdun 2013 | Ipele 4 |
NCT02328469 | Ile-iṣẹ Iṣoogun University Ljubljana|Ile-iṣẹ Iwadi Ilu Ara Slovenia | Ile-ẹkọ giga ti Ile-iwe ti Ljubljana ti Oogun, Slovenia | Ile-ẹkọ giga Harvard | Aseptic Meningitis | Oṣu Kẹfa ọdun 2014 |
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NCT00355602 | Yunifasiti ti Dundee | Tenovus Scotland | Colitis, ọgbẹ | Oṣu Keje Ọdun 2006 | Ko ṣiṣẹ fun |
NCT02606032 | Hamilton Health Sciences Corporation|Hamilton Academic Health Sciences Organization | Àrùn colitis | Oṣu Karun ọdun 2016 | Ipele 2 |
NCT01465802 | Pfizer | Akàn Ẹdọfóró Ẹdọ̀fóró Ẹ̀yin Kekere (NSCLC) | Oṣu kejila ọjọ 26, Ọdun 2011 | Ipele 2 |
NCT02623959 | Dókítà Anderson akàn ile-iṣẹ | Awọn aarun To ti ni ilọsiwaju | Awọn iṣan Pleural buburu | Oṣu Kẹrin Ọjọ 27, Ọdun 2016 | Ipele 4 |
NCT03481972 | IRCCS Policlinico S. Matteo | TTR Amyloidosis ọkan ọkan | Oṣu Kẹrin Ọjọ 11, Ọdun 2018 | Ipele 3 |
NCT00428818 | University of Texas Southwestern Medical Center | Ikolu | Oṣu Kẹjọ Ọdun 2005 | Ko ṣiṣẹ fun |
NCT01935622 | Virginia Commonwealth University | Non-ischemic Cardiomyopathy|Ìkùnà Ọkàn Systolic (NYHA II-III) | Oṣu Keje ọdun 2012 | Ipele 2 |
NCT01886560 | Ile-ẹkọ giga ti Sun Yat-sen | Oju Burns | Oṣu Kẹsan 2013 | Ipele 2 |Ibala 3 |
NCT04239755 | Ile-ẹkọ giga Damanhour | Ile-ẹkọ giga Tanta | Ipalara Ọpọlọ | Oṣu kejila ọjọ 15, Ọdun 2019 | Ipele 4 |
NCT02204254 | Center Hospitalier Universitaire de Nice | Rosacea | Oṣu Kẹta ọdun 2014 | Ko ṣiṣẹ fun |
NCT00837213 | Stiefel, Ile-iṣẹ GSK kan | GlaxoSmithKline | Irorẹ | Oṣu Kẹjọ Ọdun 2007 | Ipele 4 |
NCT03115177 | Rush University Medical Center | Osteoarthritis | Oṣu kọkanla ọdun 2015 | Ko ṣiṣẹ fun |
NCT03618108 | Cadrock Pty. Ltd.|Ile-iṣẹ fun Awọn Arun Digestive, Australia | Arun Arun inu ọkan|Chlamydophila Pneumoniae Awọn akoran | Oṣu Kẹrin Ọjọ 4, Ọdun 2018 | Ipele 2 |
NCT03435952 | MD Anderson Ile-iṣẹ Akàn | Awọn Awari afonifoji BioMed, Inc|Merck Sharp & Dohme Corp. | Neoplasm buburu ti Breast | Awọn Neoplasm buburu ti Awọn ẹya ara Digestive | Awọn Neoplasm buburu ti Ọpọlọ Oju ati Awọn ẹya miiran ti Eto aifọkanbalẹ Aarin | Awọn Neoplasm buburu ti Awọn ẹya ara abo | Awọn Neoplasm buburu ti Ile-iwe Atẹle Aisan ati Awọn aaye ti a ko ni pato Awọn aaye | Oṣu Keje 10, Ọdun 2018 | Ipele 1 |
NCT01867294 | Ile ẹkọ ẹkọ ati Iwadi Akàn Awujọ United | National Cancer Institute (NCI) | To ti ni ilọsiwaju Neoplasm Ibajẹ |Iwalapọ Ẹkọ-ara | Oṣu Kẹjọ Ọjọ 31, Ọdun 2012 | Ipele 2 |
NCT01677286 | Ile-ẹkọ giga Boston | Amyloidosis | Oṣu Keje ọdun 2012 | Ipele 2 |
NCT00511875 | Thomas Gardner|Ipilẹ Iwadi Àtọgbẹ Awọn ọmọde | Ile-iṣẹ Iṣoogun Milton S. Hershey | Àtọgbẹ Retinopathy | Oṣu Keje Ọdun 2008 | Ipele 2 |
NCT04108897 | Ile-ẹkọ giga Johns Hopkins | Rosacea | Oṣu Kẹsan Ọjọ 17, Ọdun 2019 | Ipele Ibẹrẹ 1 |
NCT00631501 | Kaunas University of Medicine | Ile-iwosan Yunifasiti, Linkoeping | Epicondylalgia Lateral (Igbowo Tẹnisi) | Ko ṣiṣẹ fun | |
NCT02203682 | Ile-ẹkọ giga ti Sun Yat-sen | Graves Ophthalmopathy|Arun Graves|Arun Oju|Arun Tairodu|Awọn Arun Eto Endocrine|Arun Oju, Ajogunba|Hyperthyroidism|Arun Aifọwọyi|Awọn Arun Ajẹsara | Oṣu Keje ọdun 2014 | Ipele 2 |
NCT02005653 | Igbimọ India ti Iwadi Iṣoogun | Filarial;Ikolu | Oṣu Kẹta ọdun 2009 | Ipele 4 |
NCT03585140 | Centro Dermatologico Dókítà Ladislao de la Pascua | Irorẹ vulgaris|Ìtúnṣe oúnjẹ | Oṣu Kẹta ọjọ 1, Ọdun 2016 | Ko ṣiṣẹ fun |
NCT02147262 | Ile-iṣẹ Iṣoogun ti Ile-ẹkọ giga Ljubljana | Ile-ẹkọ giga ti Ljubljana School of Medicine, Slovenia | Ile-ẹkọ Iṣoogun ti Vienna | Ile-ẹkọ giga Harvard | Atrophic Acrodermatitis onibaje | Oṣu Keje ọdun 2013 | Ko ṣiṣẹ fun |
NCT02220751 | University of Sao Paulo|Fundação de Amparo à Pesquisa do Estado de São Paulo | Periodontitis|Orisi 2 Àtọgbẹ mellitus | Oṣu Kẹta Ọdun 2009 | Ipele 3 |
NCT01825408 | Ile-ẹkọ giga ti North Carolina, Chapel Hill | Sinusitis | Oṣu Kẹta ọdun 2013 | Ipele 4 |
NCT02884713 | King Faisal Specialist Hospital & Iwadi ile-iṣẹ | GASTRITIS | Oṣu Kẹfa ọdun 2013 | Ko ṣiṣẹ fun |
NCT02726646 | Yunifasiti ti Campinas, Brazil | Pontificia Universidade Catolica de Sao Paulo | Periodontitis onibaje | Oṣu Kẹfa ọdun 2015 | Ipele 2 |
NCT00883818 | Samsung Medical Center | Overactive Àpòòtọ | Oṣu Kẹta ọdun 2007 | Ipele 4 |
NCT00829790 | Teva Pharmaceuticals USA | Ni ilera | Oṣu Kẹwa Ọdun 2006 | Ipele 1 |
NCT01949233 | Ile-ẹkọ giga ti Oxford | Awọn ile-iwosan Ile-ẹkọ giga ti Oxford NHS Trust | Aisan Marfan | Oṣu Kẹwa Ọdun 2013 | Ipele 2 |
NCT01518192 | Ile-iṣẹ Iṣoogun University Ljubljana|Ile-iṣẹ Iwadi Ilu Slovenia | Erythema Migrans|Àwọn Àmì Àrùn Àrùn Líyìn-Lyme | Oṣu Kẹfa ọdun 2006 | Ipele 4 |
NCT02845024 | Islam Azad University, Tehran | Àtọgbẹ mellitus Pẹlu Arun igbakọọkan | Oṣu Kẹsan 2014 | Ko ṣiṣẹ fun |
NCT01879930 | Ile-iwosan Ile-ẹkọ giga Inselspital, Berne | Ìrora Ìrora Ìbàdí Onibalẹ̀|Àrùn Ìrora àpòòtọ́ | Oṣu kọkanla ọdun 2012 | Ipele 4 |
NCT00041977 | Awọn oogun oogun CollaGenex | Irorẹ Rosacea | Oṣu Kẹfa ọdun 2002 | Ipele 3 |
NCT02341209 | Rochester General Hospital | Ẹjẹ T-cell Lymphoma|Mycosis Fungoides|Aisan Sezary | Oṣu Kẹta Ọjọ 6, Ọdun 2018 | Ipele 2 |
NCT00002872 | Ẹgbẹ Ẹkọ Onkoloji ti Ila-oorun | National Cancer Institute (NCI) | Ẹgbẹ Itọju Arun Aarin Ariwa | Metastatic Cancer | Oṣu kọkanla ọdun 1996 | Ipele 3 |
NCT03162497 | Medical University of Vienna | Àwọn Àrùn Oju Gbígbẹ|Aláìṣiṣẹ́ Gland Gland Meibomian | Oṣu Kẹta ọjọ 8, Ọdun 2018 | Ipele 4 |
NCT01418742 | Gesellschaft onírun Medizinische Innovation ?Hamatologie und Onkologie mbH|Clin Ṣe ayẹwo GmbH | Carcinoma awọ-ara | Oṣu Kẹjọ Ọdun 2011 | Ipele 2 |
NCT00980148 | Ile-ẹkọ ti Orilẹ-ede ti Ẹhun ati Awọn Arun Irun (NIAID) | Ikolu Chlamydia | Oṣu kejila ọdun 2009 | Ipele 3 |
NCT03342456 | Ile-iwosan Xiangya Kẹta ti Central South University|Livzon Pharmaceutical Group Inc.|Yung Shin Pharm.Ind. Co., Ltd. | Ulcer Duodenal Nitori Helicobacter Pylori | Oṣu kejila ọjọ 13, Ọdun 2017 | Ipele 4 |
NCT04310930 | Ile-ẹkọ giga ti Queensland | Ẹka Ilera ti Ijọba Ọstrelia | Ile-iwosan Ile-iwosan Awọn ọmọde | Cystic Fibrosis Foundation | Ile-ẹkọ giga Newcastle | Ile-ẹkọ giga Griffith | Ile-iṣẹ Iṣoogun Erasmus | Ile-ẹkọ giga Monash | Ile-ẹkọ giga ti Copenhagen | Ile-iwosan Cochin | Ilera ti Ilu Ọstrelia Gusu ati Ile-ẹkọ Iwadi Iṣoogun | Ile-ẹkọ giga ti Melbourne | James Cook University, Queensland, Australia | Murdoch Children Research Institute | Arun Ẹdọforo Nitori Mycobacteria (Ayẹwo) | Oṣu Kẹta ọdun 2020 | Ipele 2 |Ibala 3 |
NCT03709459 | Ile-iṣẹ Kirby | Ilera ti Ilu Ọstrelia Gusu ati Ile-iṣẹ Iwadi Iṣoogun | Ile-ẹkọ giga Monash | Idena STIs | Oṣu kejila ọjọ 17, Ọdun 2019 |
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NCT04067011 | Emergent BioSolutions|Iwadi Ilọsiwaju Biomedical ati Alaṣẹ Idagbasoke | Anthrax | Oṣu Kẹjọ Ọjọ 12, Ọdun 2019 | Ipele 2 |
NCT02844634 | British Columbia Center fun Arun Iṣakoso | HIV|Síphilis | Oṣu Karun ọjọ 15, Ọdun 2018 | Ipele 4 |
NCT00647959 | Mylan Pharmaceuticals | Ni ilera | Oṣu Kẹta Ọdun 2006 | Ipele 1 |
NCT00170222 | Ile-iṣẹ iṣoogun Alkmaar | Arun Idena Ẹdọforo | Oṣu Keje Ọdun 2002 | Ipele 4 |
NCT03075891 | Galderma | Rosacea | Oṣu Keje 5, Ọdun 2017 | Ipele 4 |
NCT00031499 | Ile-ẹkọ ti Orilẹ-ede ti Ẹhun ati Awọn Arun Irun (NIAID) | Sìphilis | Oṣu Kẹfa ọdun 2000 | Ipele 3 |
NCT01205464 | Ile-ẹkọ giga Linkoeping | Àìrẹ́|Ìrora Radicular|Aláìṣiṣẹ́ Ìmọ̀|Paresthesia|Paresis | Kínní 2005 | Ko ṣiṣẹ fun |
NCT01301586 | Nexgen Dermatologics, Inc. | ACNE VULGARIS | Oṣu kọkanla ọdun 2010 | Ipele 1 |Ibala 2 |
NCT02305940 | Imperial College London | Arun Idena Ẹdọforo (COPD) | Oṣu Keje ọdun 2014 | Ipele 3 |
NCT00351182 | Dong-Min Kim | Ile-iwosan Yunifasiti Chosun | Scrub Typhus | Oṣu Kẹsan 2005 | Ipele 3 |
NCT03334682 | Ile-iwosan Ile-ẹkọ giga Nantes | Irorẹ vulgaris | Oṣu Kẹta ọjọ 31, Ọdun 2018 | Ipele 3 |
NCT01788215 | Yunifasiti ti Rochester | Polycystic Ovarian Syndrome (PCOS)|Àwọn Ìwọ̀n Ìwọ̀n Ìwọ̀n Osù |Àṣejù Androgen | Oṣu kọkanla ọdun 2010 | Ipele 3 |
NCT03076281 | Sidney Kimmel Ile-iṣẹ Akàn ni Ile-ẹkọ giga Thomas Jefferson | Ile-ẹkọ giga Thomas Jefferson | Larynx|LIP|Iwo Ẹnu|Pharynx | Oṣu Kẹrin Ọjọ 3, Ọdun 2017 | Ipele 2 |
NCT00439166 | Hamilton Health Sciences Corporation | Foundation Incorporated Services Awọn Onisegun | Ile-ẹkọ giga McMaster | Arun Alzheimer | Oṣu Kẹta ọdun 2007 | Ipele 3 |
NCT02463942 | Ile-iṣẹ Iṣoogun ti Ile-ẹkọ giga Ljubljana | Ile-ẹkọ giga ti Ile-ẹkọ Oogun Ljubljana, Slovenia | Encephalitis ti o ni ami si | Oṣu Kẹsan 2014 | Ko ṣiṣẹ fun |
NCT00803842 | Northwestern University | Non Kekere Cell Ẹdọfóró akàn | Oṣu Kẹwa Ọdun 2008 | Ko ṣiṣẹ fun |
NCT02086591 | Yunifasiti ti Rochester | Ìtànkálẹ̀ Agbalagba Large B-Cell Lymphoma|Mantle Cell Lymphoma Loorekoore|Lymphoma, Follicular|Agbegbe Ipin B-Cell Lymphoma|Lymphoma Aburu - Lymphoplasmacytic|Waldenstrom Macroglobulinemia|Kekere Lymphocytic Lymphoma|Chronic Lyukphoma|Chronic Lyukphoma | Oṣu Kẹta ọdun 2014 | Ipele 2 |
NCT03980223 | Yunifasiti ti California, San Francisco | Yunifasiti ti Washington | Ile-ẹkọ ti Orilẹ-ede ti Ẹhun ati Awọn Arun Inu (NIAID) | Mayne Pharma International Pty Ltd | Ẹka Ilera ti Ilu San Francisco | Gonorrhea|Chlamydia|Síphilis | Oṣu kọkanla ọjọ 26, ọdun 2019 | Ipele 4 |
NCT00355459 | University of Texas Southwestern Medical Center | Aisan Oju gbigbẹ | Oṣu Kẹjọ Ọdun 2005 | Ko ṣiṣẹ fun |
NCT01254799 | Omar Mamdouh Shaaban|Assiut University | Ẹjẹ Uterine | Oṣu Kẹta ọdun 2008 | Ipele 3 |
NCT01547325 | NanoSHIFT LLC|Ẹ̀ka Aabo ti Orílẹ̀-Èdè Amẹ́ríkà | Awọn ọgbẹ Iṣẹ-abẹ ti a ya | Oṣu Karun ọdun 2012 | Ko ṣiṣẹ fun |
NCT00653380 | Par Pharmaceutical, Inc.|Anapharm | Lati pinnu Bioequivalence Labẹ Awọn ipo Awẹ | Oṣu Kẹsan 1999 | Ipele 1 |
NCT00635609 | Warner Chilcott | Irorẹ vulgaris | Oṣu Kẹta Ọdun 2008 | Ipele 4 |
NCT03765931 | Institut de Recherche tú le Development | Ibà | Oṣu Keje ọdun 2016 | Ipele 4 |
NCT01160640 | Harold Wiesenfeld | Ile-ẹkọ ti Orilẹ-ede ti Ẹhun ati Awọn Arun Inu (NIAID) | Ile-ẹkọ giga ti Pittsburgh | Arun Irun Ibadi | Oṣu kọkanla ọdun 2010 | Ipele 2 |
NCT01756833 | Yunifasiti ti Maryland, Baltimore | Ile-ẹkọ ti Orilẹ-ede lori Agbo (NIA) | Aneurysm | Oṣu Karun ọdun 2013 | Ipele 2 |
NCT00688064 | Galderma | Àìdá Irorẹ vulgaris | Oṣu Kẹjọ Ọdun 2008 | Ipele 3 |
NCT01320033 | Galderma | Irorẹ vulgaris | Oṣu Kẹta Ọjọ 29, Ọdun 2011 | Ipele 2 |
NCT03397004 | Ile-iwosan St. Michael's, Toronto|Ile-ẹkọ Imọ-ara ti Barrow | Ile-ẹkọ giga Duke | Ile-ẹkọ Feinstein fun Iwadi Iṣoogun | Ile-ẹkọ giga ti Pittsburgh | Ile-iṣẹ Sayensi Ilera Sunnybrook | Telangiectasia Hemorrhagic Hemorrhagic (HHT) | Oṣu Kẹsan Ọjọ 12, Ọdun 2018 | Ipele 2 |
NCT01635530 | Ile-iwosan Yunifasiti ti Turku | Neuroborreliosis Lyme | Oṣu Kẹjọ Ọdun 2012 | Ipele 4 |
NCT03727620 | Mohammed V Souissi University | Periodontitis ibinu | Oṣu Kẹta ọjọ 6, Ọdun 2014 | Ipele 1 |Ibala 2 |
NCT02688738 | Rothman Institute Orthopedics | Propionibacterium | Oṣu Kẹta ọdun 2015 | Ko ṣiṣẹ fun |
NCT00358462 | Yunifasiti ti Washington | Ile-ẹkọ ti Orilẹ-ede ti Ẹhun ati Awọn Arun Arun (NIAID) | Urethritis | Oṣu Kẹta ọdun 2007 | Ipele 3 |
NCT02864550 | British Columbia Center fun Arun Iṣakoso | Syphilis|Àkóràn Ìbálòpọ̀ | Oṣu Kẹjọ Ọjọ 15, Ọdun 2019 | Ipele 4 |
NCT01595594 | University of Sao Paulo|Fundação de Amparo à Pesquisa do Estado de São Paulo | Arun igbakọọkan|Atọgbẹ Iru 2 | Oṣu Kẹta ọdun 2010 | Ipele 3 |
NCT00964834 | PharmAthene, Inc.| Awọn ile-iṣẹ Ilera ti Orilẹ-ede (NIH)|Medarex|Quintiles, Inc.|Ẹka ti Ilera ati Awọn Iṣẹ Eda Eniyan | Anthrax | Oṣu Keje Ọdun 2009 | Ipele 1 |
NCT01809444 | Ile-ẹkọ giga ti Sun Yat-sen | Awọn Opthalmopathies Iṣọkan Tairodu | Oṣu kọkanla ọdun 2012 | Ipele 2 |Ibala 3 |
NCT01590082 | MD Anderson Ile-iṣẹ Akàn | Awọn ile-iṣẹ Ilera ti Orilẹ-ede (NIH) | Ile-iṣẹ Akàn ti Orilẹ-ede (NCI) | Melanoma | Oṣu kọkanla ọdun 2012 | Ipele 1 |Ibala 2 |
NCT00207584 | Awọn ile-iṣẹ fun Iṣakoso ati Idena Arun | Mycoplasma Pneumoniae | Oṣu Kini Ọdun 1994 | Ko ṣiṣẹ fun |
NCT00775177 | Ranbaxy Laboratories Limited|Ranbaxy Inc. | Ni ilera | Oṣu Kẹfa ọdun 2005 | Ko ṣiṣẹ fun |
NCT03462329 | University Medical Center Ljubljana | Erythema Migrans | Oṣu Kẹfa Ọjọ 1, Ọdun 2018 | Ko ṣiṣẹ fun |
NCT00000403 | Ile-ẹkọ giga Indiana | Ile-ẹkọ ti Orilẹ-ede ti Arthritis ati Ẹjẹ-ara ati Awọn Arun Awọ (NIAMS) | Ile-ẹkọ ti Orilẹ-ede lori Aging (NIA) | Osteoarthritis | Oṣu Kẹsan 1996 | Ipele 3 |
NCT03508232 | Ile-ẹkọ giga ti Alberta | Ile-iwosan Royal Alexandra | Apa ST Igbega Miyocardial Infarction|Ikuna ọkan | Oṣu Kẹta Ọjọ 6, Ọdun 2020 | Ipele 2 |
NCT02553473 | Ile-iwosan Sorlandet HF | Neuroborreliosis, Borrelia Burgdorferi | Oṣu Kẹwa Ọdun 2015 | Ipele 3 |
NCT02207556 | Ile-iwe iṣoogun ti Wisconsin | Amyloidosis eto eto akọkọ | Oṣu Kẹjọ Ọjọ 1, Ọdun 2014 | Ipele 2 |
NCT01783106 | Ile-iwosan Ile-ẹkọ giga ti Royal Liverpool | Ẹgbẹ Orilẹ-ede fun Colitis ati Arun Crohn | Ile-ẹkọ ti Orilẹ-ede fun Iwadi Ilera, United Kingdom | Arun Crohn | Oṣu Kẹta Ọjọ 1, Ọdun 2014 | Ipele 2 |
NCT00353743 | Ile iwosan de Clinicas de Porto Alegre | Iṣẹyun, Septic | Oṣu Karun ọdun 2006 | Ko ṣiṣẹ fun |
NCT01727973 | Ile-ẹkọ giga ti Sun Yat-sen | Graves Ophthalmopathy|Arun Graves|Arun Oju|Arun Tairodu|Awọn Arun Eto Endocrine|Arun Oju, Ajogunba|Hyperthyroidism|Arun Aifọwọyi|Awọn Arun Ajẹsara | Oṣu Kẹwa Ọdun 2012 | Ipele 1 |Ibala 2 |
NCT00857038 | Ile-iṣẹ Iṣoogun Alkmaar | Ile-iṣẹ Iṣoogun University Leiden | Ile-ẹkọ giga ti Amsterdam | Àrùn Àrùn Ìdènà Ẹ̀dọ̀fóró|Ìgbóguntini|Ẹ̀dọ̀fóró Emphysema | Oṣu Kẹrin Ọjọ 2009 | Ipele 4 |
NCT02774993 | Ile-iwosan Ile-ẹkọ giga ti Orilẹ-ede, Singapore | Ile-iwosan Tan Tock Seng | Ile-ẹkọ giga ti Orilẹ-ede, Singapore | A * Irawọ | iko | Oṣu Kẹsan 2015 | Ipele 2 |
NCT03474458 | IRCCS Policlinico S. Matteo | Ẹjẹ ọkan AL Amyloidosis | Oṣu Kẹta Ọjọ 11, Ọdun 2019 | Ipele 2 |Ibala 3 |
NCT02874430 | Sidney Kimmel Ile-iṣẹ Akàn ni Ile-ẹkọ giga Thomas Jefferson | Ile-ẹkọ giga Thomas Jefferson | Carcinoma Breast|Ẹyin Ẹjẹ Kede Adenocarcinoma|Endometrial Serous Adenocarcinoma|Uterine Corpus Cancer|Uterine Corpus Carcinosarcoma | Oṣu Kẹfa Ọjọ 8, Ọdun 2016 | Ipele 2 |
NCT00016835 | Ile-ẹkọ giga ti Michigan | Ile-ẹkọ ti Orilẹ-ede ti Dental ati Iwadi Craniofacial (NIDCR) | Arun igbakọọkan | Àtọgbẹ mellitus, Iru 2 | Oṣu Kẹwa Ọjọ 17, Ọdun 2001 | Ipele 2 |
NCT00064766 | Eunice Kennedy Shriver National Institute of Health Child and Human Development (NICHD) | Ẹjẹ Ẹjẹ Endometrial|Arun Igbakọọkan | Oṣu Kẹta ọdun 2003 | Ipele 4 |
NCT00803452 | Yunifasiti ti Louisville | Blepharitis | Oṣu Keje Ọdun 2008 | Ipele 4 |
NCT01434173 | Bayer|RTI Awọn solusan Ilera | Ifarapa Ẹdọ ti O jẹ oogun | Oṣu Keje Ọdun 2001 |
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NCT00126204 | Barnes-Juu Hospital | Aortic Aneurysm | Oṣu Kẹta Ọdun 2004 | Ko ṣiṣẹ fun |
NCT01917721 | Hawaii Pacific Health | Arun Kawasaki|Aneurysm | Oṣu Kẹwa Ọdun 2013 | Ipele 2 |
NCT02775695 | Ile-iwe iṣoogun ti Wisconsin | Akàn Pancreatic Resectable | Oṣu Kẹrin Ọjọ 3, Ọdun 2017 | Ipele 2 |
NCT03824340 | Ile-iwosan Aljazeera | Àìbímọ | Oṣu Kẹta Ọjọ 30, Ọdun 2019 | Ko ṣiṣẹ fun |
NCT01847976 | Ile-iṣẹ Iwadi Ile-iwosan Ottawa | Foundation Canadian Breast Cancer Foundation | Irora | Oṣu Kẹjọ Ọdun 2013 | Ipele 2 |
NCT02850913 | Ile-ẹkọ giga Makerere | Ile-ẹkọ giga ti Oxford | Awọn ikọlu | Oṣu Kẹsan Ọjọ 5, Ọdun 2016 | Ipele 2 |
NCT00764361 | NanoSHIFT LLC | Ọgbẹ Ẹsẹ Àtọgbẹ | Oṣu Kẹta ọdun 2009 | Ipele 2 |
NCT02036528 | Royer Biomedical, Inc. | Àrùn Ẹsẹ Àtọgbẹ | Oṣu Kẹta ọdun 2014 | Ipele 1 |Ibala 2 |
NCT01661985 | Igbimọ Agbegbe Ostergotland, Sweden | Ile-ẹkọ Serum State | Urethritis|Cervicitis|Àkóràn Mycoplasma Ẹ̀yà | Chlamydia Trachomatis | Oṣu Kẹta ọdun 2010 | Ipele 4 |
NCT01380483 | Par Pharmaceutical, Inc.|Anapharm | Lati pinnu Bioequivalence Labẹ Awọn ipo Awẹ | Oṣu Kẹta ọdun 2000 | Ipele 1 |
NCT00648180 | Mylan Pharmaceuticals | Ni ilera | Oṣu Keje Ọdun 2005 | Ipele 1 |
NCT01426269 | Galderma Laboratories, LP | Rosacea | Oṣu Kẹsan 2011 | Ipele 4 |
NCT02753426 | Yunifasiti ti California, San Francisco | Arun Kidinrin Onibaje|Arun inu ọkan | Oṣu Kẹrin Ọjọ 2016 | Ipele 1 |
NCT02583282 | Postgraduate Institute of Medical Education ati Iwadi | Ìfàjẹ̀sínilára Pleural | Oṣu Kẹjọ Ọjọ 1, Ọdun 2015 | Ko ṣiṣẹ fun |
NCT02927496 | Agbofinro fun Ilera Kariaye|Ile-iṣẹ Amẹrika fun Idagbasoke Kariaye (USAID) | Lymphedema|Lymphatic Filariasis|Filariasis | Oṣu Kẹfa Ọjọ 19, Ọdun 2018 | Ipele 3 |
NCT00652795 | Par Pharmaceutical, Inc.|Anapharm | Lati pinnu Bioequivalence Labẹ Awọn ipo Awẹ | Oṣu Keje Ọdun 2004 | Ipele 1 |
NCT03956212 | Ile-iṣẹ Iṣoogun ti Ile-ẹkọ giga Ljubljana | Ile-ẹkọ giga ti Ile-ẹkọ Oogun Ljubljana, Slovenia | Erythema Migrans | Oṣu Kẹfa Ọjọ 1, Ọdun 2017 | Ko ṣiṣẹ fun |
NCT00855595 | Bayer | Papulopustular Rosacea | Oṣu Kẹta ọdun 2009 | Ipele 4 |
NCT03457636 | Derm Iwadi, PLLC | Irorẹ | Oṣu Kẹta Ọjọ 19, Ọdun 2018 | Ipele 4 |
NCT02894268 | Sir Run Run Shaw Hospital | Helicobacter Pylori Ikolu | Oṣu Kẹta ọdun 2016 | Ipele 4 |
NCT03465774 | MD Anderson Ile-iṣẹ Akàn | Ile-ẹkọ Akàn ti Orilẹ-ede (NCI) | Ìfàjẹ̀sínilára Pleural | Oṣu Kẹta Ọjọ 8, Ọdun 2018 | Ipele Ibẹrẹ 1 |
Ilana kemikali
Igbero18Awọn iṣẹ akanṣe Igbelewọn Iṣeduro Didara eyiti o ti fọwọsi4, ati6ise agbese ni o wa labẹ alakosile.
Eto iṣakoso didara agbaye ti ilọsiwaju ti fi ipilẹ to lagbara fun tita.
Abojuto didara n ṣiṣẹ nipasẹ gbogbo igbesi aye ọja lati rii daju didara ati ipa itọju ailera.
Ẹgbẹ Aṣoju Iṣeduro Ọjọgbọn ṣe atilẹyin awọn ibeere didara lakoko ohun elo ati iforukọsilẹ.